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CEREP Inc hill software
Hill Software, supplied by CEREP Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hill+software/hill+software/pm40222476-428-1-9
Average 90 stars, based on 1 article reviews
hill software - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT 2 Receptor Agonist.
Article Snippet: Structure−activity studies of 4-substituted-2,5-dimethoxyphenethylamines led to the discovery of 2,5-dimethoxy-4-thiotrifluoromethylphenethylamines, including CYB210010, a potent and long-acting serotonin 5-HT2 receptor agonist.. CYB210010 exhibited high agonist potency at 5-HT2A and 5-HT2C receptors, modest selectivity over 5-HT2B, 5-HT1A, 5-HT6, and adrenergic α2A receptors, and lacked activity at monoamine transporters and over 70 other proteins.. CYB210010 (0.1−3 mg/kg) elicited a head-twitch response (HTR) and could be administered subchronically at threshold doses without behavioral tolerance.

Article Title: Preclinical evaluation of ELP‐004 in mice
Article Snippet: The IC 50 values and Hill coefficients (nH) were determined by non‐linear regression analysis of the competition curves generated with mean replicate values using Hill equation curve fitting using software developed at CEREP (Hill software).

Article Title: RE104: Synthesis and Activity of a Novel Serotonergic Psychedelic Prodrug of 4-Hydroxy- N , N -diisopropyltryptamine
Article Snippet: For all receptor pharmacology assays, data were analyzed with software developed at Cerep (Hill software, Celle-Lévescault, France) and validated by comparison with data generated by the commercial software SigmaPlot 4.0 for Windows (1997 by SPSS Inc.).

Article Title: Xelaglifam, a novel GPR40/FFAR1 agonist, exhibits enhanced β-arrestin recruitment and sustained glycemic control for type 2 diabetes.
Article Snippet: Xelaglifam, developed as a GPR40/FFAR1 agonist, induces glucose-dependent insulin secretion and reduces circulating glucose levels for Type 2 diabetes treatment.. This study investigated the effects of Xelaglifam in comparison with Fasiglifam on the in vitro/in vivo anti-diabetic efficacy and selectivity, and the mechanistic basis.. In vitro studies on downstream targets of Xelaglifam were performed in GPR40-expressing cells.

Article Title: RE104: Synthesis and Activity of a Novel Serotonergic Psychedelic Prodrug of 4-Hydroxy- N , N -diisopropyltryptamine.
Article Snippet: For all receptor pharmacology assays, data were analyzed with software developed at Cerep (Hill software, CelleLev́escault, France) and validated by comparison with data generated by the commercial software SigmaPlot 4.0 for Windows (1997 by SPSS Inc.).


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